New pfizer drug shows promise against tough cancers

NCT ID NCT04553133

Ongoing Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called PF-07104091 in people with advanced small cell lung cancer, ovarian cancer, or certain breast cancers that have not responded to prior treatments. The goal is to find the safest dose and see if the drug shrinks tumors, either alone or with other medicines. About 157 participants will take part in this early-phase trial.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm fallopian tube cancer hormone receptor-positive breast cancer non-small cell lung carcinoma ovarian cancer ovarian carcinoma primary peritoneal carcinoma small cell lung carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER OVARIAN CANCER SMALL CELL LUNG CANCER

Contacts and locations

Locations

Centro de Investigaciones Medicas y Desarrollo LC

Buenos Aires, Buenos Aires F.D., 1113, Argentina
Complex Oncology Center - Plovdiv EOOD

Plovdiv, 4004, Bulgaria
Complex Oncology Center - Shumen

Shumen, 9700, Bulgaria
Dana-Farber Cancer Institute - Chestnut Hill

Newton, Massachusetts, 02459, United States
Des Moines Oncology Research Association

Des Moines, Iowa, 50309, United States
Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, 200032, China
Laura & Isaac Perlmutter Cancer Center - NYU ACC

New York, New York, 10016, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Medical Oncology & Hematology Associates DBA Mission Cancer and Blood

Clive, Iowa, 50325, United States
Medical Oncology & Hematology Associates DBA Mission Cancer and Blood

Des Moines, Iowa, 50309, United States
Medical Oncology & Hematology Associates DBA Mission Cancer and Blood

Des Moines, Iowa, 50314, United States
Memorial Sloan Kettering Cancer Center (IDS Pharmacy)

Long Island City, New York, 11101, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
NYU Langone Medical Center (Tisch Hospital)

New York, New York, 10016, United States
Norton Brownsboro Hospital

Louisville, Kentucky, 40241, United States
Norton Cancer Institute, Audubon

Louisville, Kentucky, 40217, United States
Norton Cancer Institute, Brownsboro Campus

Louisville, Kentucky, 40241, United States
Norton Cancer Institute, St. Matthews Campus

Louisville, Kentucky, 40207, United States
Norton Hospital

Louisville, Kentucky, 40202, United States
Tianjin Medical University Cancer Institute & Hospital

Tianjin, Tianjin Municipality, 300060, China
UVA Breast Care Center

Charlottesville, Virginia, 22911, United States
White Plains Hospital

White Plains, New York, 10601, United States

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