New drug combo targets Hard-to-Treat blood cancers

NCT ID NCT03479268

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new two-drug combination (pevonedistat and ibrutinib) in adults with chronic lymphocytic leukemia or non-Hodgkin lymphoma that has returned or no longer responds to standard therapy. The main goal is to find the safest dose and understand side effects. About 18 participants will take part at a single center.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14263, United States

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