New imaging agent could shed light on Cholesterol's role in disease
NCT ID NCT04532489
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study is testing a new radioactive tracer called [18F]FNP-59 to see if it can safely and clearly image cholesterol in the adrenal glands using PET scans. Six healthy volunteers will receive a tiny, non-therapeutic dose of the tracer. The goal is to improve imaging for conditions like high blood pressure that involve cholesterol trafficking.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
FNP-59 (a radioactive tracer for PET scans)
What this could lead to
If successful, this could lead to a better imaging method to study cholesterol-related conditions like high blood pressure or adrenal disorders.
What could go wrong
This is a very early, small study with only 6 healthy participants, so it may not translate to patients. The tracer's safety and effectiveness are still unknown.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••