New PET scan tracer could spot breast cancer better

NCT ID NCT03863457

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study is testing a new radioactive tracer called [18F]F-GLN for PET/CT scans in people with breast cancer. The goal is to see how well this tracer highlights tumors and to gather safety information. Up to 40 adults with known or suspected breast cancer will receive one injection of the tracer and undergo imaging. The results will not be used to guide treatment decisions, but may help develop better ways to detect and understand breast cancer.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
[18F]F-GLN (a radioactive tracer for PET/CT imaging)
What this could lead to
If successful, this could lead to a new imaging method to better detect and characterize breast cancer subtypes, potentially guiding more personalized treatment.
What could go wrong
This is a very early, small pilot study (40 people) focused on imaging, not treatment. The tracer may not provide clear or useful images, and results may not apply to all breast cancers.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

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