Custom-Made vaccine targets tough cancers in early trial

NCT ID NCT04266730

First seen Jan 16, 2026 · Last updated May 09, 2026 · Updated 8 times

Summary

This early-phase trial tested a personalized vaccine (PANDA-VAC) made from a patient's own tumor markers, given alongside the immunotherapy drug pembrolizumab. It involved 6 adults with advanced squamous lung or head/neck cancers that could not be cured. The main goal was to check safety and side effects, not to cure the disease.

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Contacts and locations

Locations

  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.