Smarter radiation aims to cut side effects in prostate cancer relapse
NCT ID NCT07515651
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a personalized radiation approach for men whose prostate cancer has returned after surgery. Using PSMA PET scans, doctors will give higher radiation doses to active cancer spots and lower doses to healthy areas, all in just 5 treatments over two weeks. The goal is to reduce side effects while keeping the cancer under control. Fifty participants will be followed for five years to track side effects and cancer recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Image-guided radiotherapy (SBRT) with PSMA PET-based dose adjustment
What this could lead to
If successful, this approach could reduce treatment side effects while maintaining high cure rates for prostate cancer that has returned after surgery.
What could go wrong
This is a small, early-phase trial (50 participants) without a comparison group, so results may not apply broadly. There is also a risk that lowering radiation to some areas might allow cancer to return.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University Health Network - Princess Margaret Cancer Center
Toronto, Ontario, M5G 2M9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••