Custom drug testing: a new way to match RA patients with their ideal treatment

This study aims to learn which FDA-approved rheumatoid arthritis (RA) medication works best for each individual patient. Researchers will enroll 18 adults with newly diagnosed, moderately to severely active RA. Participants will try up to four different RA drugs in a random order and report their pain, symptoms, and quality of life through regular questionnaires. The goal is to see if a personalized N-of-1 trial design can help doctors choose the most effective treatment for each person.