New trial aims to customize breast cancer radiation to cut harmful side effects

NCT ID NCT06382818

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether personalizing the dose and schedule of radiation therapy after breast cancer surgery can reduce long-term side effects like scarring (fibrosis) and radiation-induced cancers, while still preventing the cancer from coming back. The trial will enroll 854 women with invasive breast cancer who have had surgery. Doctors will choose from several standard radiation schedules based on each patient's risk of recurrence and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiotherapy (IMRT) with different dosing schedules

What this could lead to

If successful, this could lead to fewer long-term side effects like fibrosis and sarcoma, while still effectively controlling breast cancer recurrence.

What could go wrong

This is a non-randomized study, so results may be less definitive. The personalized approach may not reduce side effects as hoped, and long-term follow-up is needed to confirm safety.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut Du Cancer de Montpellier

    RECRUITING

    Montpellier, France

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••