Can targeting the right brain spot boost depression treatment?

NCT ID NCT05224063

First seen Nov 05, 2025 · Last updated May 21, 2026 · Updated 25 times

Summary

This study tested whether personalizing the location of transcranial magnetic stimulation (TMS) based on an individual's brain network could improve its effects on depression. Fifty adults with major depression received a single session of TMS targeted to their central executive network, standard scalp location, or a sham (fake) treatment. The goal was to measure brain changes, not to treat depression directly, and results will inform a future clinical trial.

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Contacts and locations

Locations

  • Stanford University

    Stanford, California, 94305, United States

Conditions

Explore the condition pages connected to this study.