Nerve block may cut opioid need in bile duct procedure, small study suggests

NCT ID NCT06618781

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed observational study in 52 adults compared standard sedation alone to sedation plus a lateral quadratus lumborum block (an injection of numbing medicine near the lower back muscles) during percutaneous transhepatic cholangiography, a procedure to diagnose or treat bile duct blockages. The main goal was to see if the block reduces the amount of opioid painkiller needed during the procedure. Researchers also tracked pain scores, recovery time, and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

bupivacaine and lidocaine (local anesthetics)

What this could lead to

If results are positive, this could support using quadratus lumborum blocks to reduce opioid needs and improve recovery in similar procedures.

What could go wrong

This is a small observational study (52 patients) with no randomization or blinding, so results may be influenced by bias and may not apply broadly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara Etlik City Hospital

    Altındağ, Ankara, 06000, Turkey (Türkiye)