Gum graft boosts implant infection repair?

NCT ID NCT04323540

Completed Disease control Sponsor: George Eastman Dental Hospital, Italy Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two surgical treatments for peri-implantitis, a serious gum infection around dental implants. Both methods used bone grafting, but one group also received a soft tissue graft from the palate. The trial involved 32 adults and measured gum health, bone loss, and patient satisfaction. Results will help determine if adding the soft tissue graft improves outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgical procedure (bone graft with or without soft tissue graft)
What this could lead to: If successful, this could lead to a more effective surgical approach for treating peri-implantitis, potentially improving implant survival and gum health.
What could go wrong: This is a small, early-stage trial with only 32 participants, so results may not apply to everyone. The added surgery for the soft tissue graft also carries risks like pain, swelling, or graft failure.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERI IMPLANTITIS

Contacts and locations

Locations

George Eastman Dental Hospital

Roma, 00100, Italy

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