Vitamin d levels in gum fluid may predict implant trouble

NCT ID NCT07280754

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will measure vitamin D and a natural antimicrobial peptide called LL-37 in the fluid around dental implants. Researchers want to see if these levels can help detect early signs of peri-implantitis or mucositis. The study includes 72 adults aged 18-65 who have had implant-supported prostheses for at least one year. If successful, it could lead to earlier diagnosis and better management of these common implant complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to earlier diagnosis of peri-implant diseases, potentially reducing treatment costs and improving outcomes.

What could go wrong

This is an observational study with only 72 participants, so results may not apply broadly. It measures biomarkers, not treatments, so direct patient benefit is not guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.