New lymphoma cocktail shows promise in early trial

NCT ID NCT04231877

First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 26 times

Summary

This early-stage trial is testing whether adding two targeted drugs (polatuzumab vedotin and glofitamab) to standard chemotherapy can safely treat aggressive B-cell non-Hodgkin lymphoma that hasn't been treated before. About 56 adults with fast-growing lymphoma will receive the combination to see how well they tolerate it. The goal is to find a more effective upfront treatment for this serious blood cancer.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIGH GRADE B-CELL LYMPHOMA WITH MYC AND BCL2 AND/OR BCL6 REARRANGEMENTS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.