New hope for aggressive lymphoma: targeted drug combo under study

NCT ID NCT04231877

First seen Nov 01, 2025 · Last updated Jun 04, 2026 · Updated 36 times

Summary

This early-phase study tests whether adding the targeted drug polatuzumab vedotin (with or without glofitamab) to standard chemotherapy is safe for people with untreated, aggressive B-cell lymphoma. About 56 participants will receive the combination to see how well they tolerate it. The goal is to find a more effective upfront treatment for this fast-growing cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.