Can a vaccine stop head and neck cancer from coming back?
NCT ID NCT03821272
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a vaccine called PepCan in 17 people who had head and neck cancer and were in remission. The goal was to see if the vaccine is safe and can reduce the chance of the cancer returning. Participants received seven injections of either PepCan or a placebo over about two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PepCan (HPV 16 E6 peptides combined with Candin)
What this could lead to
If it works, this could point toward a way to lower the chance of head and neck cancer coming back after remission.
What could go wrong
This is a very small early-phase trial with only 17 participants, so results may not apply to everyone. The vaccine may not reduce recurrence or could cause side effects.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEAD AND NECK CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205, United States