New nerve block could replace morphine for hip surgery pain

NCT ID NCT07449585

Not yet recruiting Symptom relief Sponsor: Medical University of Gdansk Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a nerve block (PENG) to spinal morphine for pain after total hip replacement. About 180 adults will be randomly assigned to one of three groups: PENG block, spinal morphine, or spinal anesthesia alone. The goal is to see which method provides better pain control with fewer side effects like nausea and itching.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ropivacaine and dexamethasone (PENG block) vs. morphine (intrathecal)
What this could lead to: If the PENG block works better, it could offer a safer way to manage pain after hip replacement, reducing the need for opioids and their side effects.
What could go wrong: This is a small, early-stage trial that hasn't started yet. The nerve block may not be as effective as morphine, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP DISEASE HIP REPLACEMENT, TOTAL PERIOPERATIVE ANALGESIA POSTOPERATIVE PAIN

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