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New pain block could cut morphine use after hip surgery

NCT ID NCT05250492

Symptom relief Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial compares two ways to manage pain during hip replacement surgery: an ultrasound-guided nerve block (PENG block) versus injecting anesthetic directly into the joint. The study includes 60 adults scheduled for anterior hip replacement under general anesthesia. The main goal is to see which method reduces the need for morphine right after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ultrasound-guided PENG block (pericapsular nerve group block) with anesthetic
What this could lead to
If the PENG block proves better, it could become the standard method for controlling pain after hip replacement, reducing reliance on morphine.
What could go wrong
This is a small, early-stage comparison, so results may not apply to all patients or surgical approaches. The PENG block might not offer significant advantages over the simpler infiltration method.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Mar 2022

Finished

May 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient, male or female, over 18 years old. * Patient scheduled for anterior hip prosthesis. * Affiliated patient or beneficiary of a social security scheme. * Patient having been informed and having signed a free and informed consent. Exclusion Criteria: * Patient with a contraindication to local anesthesia. * Patient with a high level of dependence, defined by level 1 or 2 of the Iso-Ressources Group (GIR). * Patient participating in another clinical study. * Protected patient: adult under guardianship, curatorship or other legal protection, deprived of freedom by judicial or administrative decision. * Pregnant, breastfeeding or parturient woman. * Patient hospitalized without consent.

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesia Hip prosthesis Peng block

Contacts and locations

Locations

  • Jean-François Oudet

    Lanester, 56600, France

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