Could a diabetes drug help fight head and neck cancer?
NCT ID NCT04414540
First seen Jan 04, 2026 · Last updated Apr 30, 2026 · Updated 17 times
Summary
This study tests whether adding the diabetes drug metformin to the immunotherapy drug pembrolizumab can help shrink tumors in people with advanced head and neck cancer that has spread or come back. The goal is to see if this combination can boost the body's natural killer cells to fight the cancer more effectively. The study enrolled 20 adults whose cancer could not be cured with surgery or radiation.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Cincinnati Medical Center
Cincinnati, Ohio, 45219, United States
Conditions
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