New combo shows promise for tough lung cancers

NCT ID NCT03003468

First seen Jan 23, 2026 · Last updated May 12, 2026 · Updated 17 times

Summary

This study tested a combination of two drugs—pembrolizumab (an immunotherapy) and Imprime PGG (a yeast-based immune booster)—in 35 adults with advanced non-small cell lung cancer that had worsened after initial therapy. The goal was to see if the combo could shrink tumors or slow cancer growth. While not a cure, the approach aims to help control the disease and improve outcomes for patients with limited options.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Indiana Univeristy Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202, United States

  • Penn State Cancer Institute

    Hershey, Pennsylvania, 17033, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States

  • University of Iowa Hospital and Clinics

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.