Immune system weapon tested against tough brain cancers
NCT ID NCT02658279
Summary
This small, early-stage study is testing whether the immunotherapy drug pembrolizumab can help control the growth of recurrent malignant brain tumors (gliomas) in a specific group of patients. The drug works by activating the body's own immune system to attack cancer cells. Researchers are looking to see if the treatment can shrink tumors or stop them from growing for at least six months in patients whose tumors have a high number of genetic mutations.
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Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Md Anderson Cancer Center
Houston, Texas, 77030, United States
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Memorial Sloan Kettering Bergen
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
Basking Ridge, New Jersey, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States
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University of California San Francisco
San Francisco, California, 94143, United States
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University of California, Los Angeles
Los Angeles, California, 90095, United States
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University of Miami
Miami, Florida, United States
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University of Utah
Salt Lake City, Utah, 84112, United States
Conditions
Explore the condition pages connected to this study.