Triple therapy shows promise in shrinking sarcomas before surgery
NCT ID NCT06128863
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests whether combining an immunotherapy drug (pembrolizumab) with another immune-boosting protein (eftilagimod alpha) and radiation therapy can shrink soft tissue sarcomas before surgery. About 40 adults with high-risk, non-spread sarcomas will receive this combination, then have their tumor removed to see how much of it has been destroyed. The goal is to improve outcomes, but ongoing monitoring and potential long-term treatment may still be needed.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Maria Sklodowska-Curie National Research Institute of Oncology
Warsaw, 00-738, Poland