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Mesh vs. muscle flap: which rebuilds pelvic floor better after cancer surgery?

NCT ID NCT01347697

Completed Disease control Sponsor: Umeå University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two methods to repair the pelvic floor after removing the rectum for advanced rectal cancer. One method uses a biological mesh made from pig collagen, the other uses a flap of muscle from the buttock. The goal was to see which approach leads to better physical function six months after surgery. The trial involved 91 adults and was completed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
porcine acellular dermal collagen implant (biological mesh)
What this could lead to
If the biological mesh works better, it could offer a simpler, less painful recovery for patients after rectal cancer surgery.
What could go wrong
This is a small, completed trial with only 91 participants, so results may not apply to everyone. The mesh might not improve physical performance as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEFECT OF FLOOR OF LESSER PELVIS RECTAL CANCER

Contacts and locations

Locations

  • Karolinska University Hospital, Solna

    Stockholm, 171 76, Sweden

  • Oulu University Hospital

    Oulu, Finland

  • Skåne Universtiy Hospital

    Malmö, 20502, Sweden

  • Sunderby County Hospital

    Luleå, 971 80, Sweden

  • Umeå University Hospital, Department of Surgical and Perioperative Sciences

    Umeå, 901 85, Sweden

  • Uppsala University Hospital

    Uppsala, 751 85, Sweden

  • Västmanlands Sjukhus Västerås

    Västerås, 72189, Sweden

  • Östersund Hospital

    Östersund, 831 83, Sweden

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