New hope for myelofibrosis: experimental drug combo tested in japan

NCT ID NCT07340138

First seen Jan 17, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This early-stage study tests whether adding the experimental drug pelabresib to the standard treatment ruxolitinib is safe for Japanese adults with myelofibrosis, a rare bone marrow cancer. Only 6 participants will receive the combination to check for side effects and how the drug behaves in the body. The goal is to find a safe dose for future studies, not to cure the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Novartis Investigative Site

    RECRUITING

    Kamogawa, Chiba, 296-8602, Japan

  • Novartis Investigative Site

    RECRUITING

    Sapporo, Hokkaido, 0030006, Japan

  • Novartis Investigative Site

    RECRUITING

    Kamakura, Kanagawa, 247-8533, Japan

  • Novartis Investigative Site

    RECRUITING

    Bunkyo Ku, Tokyo, 1138431, Japan

  • Novartis Investigative Site

    RECRUITING

    Chūō, Yamanashi, 409-3898, Japan

  • Novartis Investigative Site

    RECRUITING

    Kumamoto, 862-8655, Japan

Conditions

Explore the condition pages connected to this study.