Can friends help stop HIV? brazil trial lets peers deliver PrEP

NCT ID NCT06661356

Not yet recruiting Prevention Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether having trained peer workers deliver HIV prevention medication (PrEP) in community settings helps more young people in Brazil start and stay on PrEP compared to standard clinic care. About 1,400 youth aged 15-24 who are sexually active and not currently using PrEP will be randomly assigned to either peer-led community PrEP or usual care. The goal is to see if this approach increases PrEP use and adherence over 13 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral PrEP (daily or event-driven)
What this could lead to: If successful, this could show that peer-led PrEP delivery improves HIV prevention access and adherence among young people in Brazil.
What could go wrong: This is a behavioral intervention trial, not testing a new drug. Results may not apply to other settings, and adherence depends on peer relationships.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV PRE-EXPOSURE PROPHYLAXIS (PREP)

Contacts and locations

Locations

Federal University of Bahia

Salvador, Estado de Bahia, Brazil
University of São Paulo

São Paulo, São Paulo, Brazil

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