Do Kids' immune systems crash like Adults' after severe infection? new study investigates

NCT ID NCT02848144

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether children with severe infectious shock develop immune suppression, similar to what is seen in adults. Researchers measured immune markers in 105 children admitted to intensive care and compared them to healthy children having surgery. The goal was to understand how the immune system responds and whether this affects recovery and risk of additional infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could confirm that children with severe infectious shock develop immune suppression similar to adults, guiding future treatments.

What could go wrong

This is an observational study with only 105 participants, so results may not apply to all children. It does not test any treatment, so direct benefits are unlikely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Sepsis toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospices Civils de Lyon

    Lyon, France