Promising Short-Course chemo for kids with hodgkin lymphoma

NCT ID NCT00846742

First seen Jan 11, 2026 · Last updated Jun 20, 2026 · Updated 25 times

Summary

This phase 2 trial tests a shorter, intensive chemotherapy regimen (Stanford V) for children and young adults with favorable-risk Hodgkin lymphoma. Those who still have signs of cancer after 8 weeks of chemo also receive low-dose radiation to the affected areas. The goal is to see if this approach can improve the complete response rate compared to a previous treatment plan, while reducing overall treatment burden.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital of Illinois at OSF St. Francis Medical Center

    Peoria, Illinois, 61637, United States

  • Dana-Farber Harvard Cancer Center

    Boston, Massachusetts, 02115, United States

  • Maine Children's Cancer Program (MCCP)

    Scarborough, Maine, 04074, United States

  • Packard Children's Hospital, Stanford University

    Palo Alto, California, 94304, United States

  • Rady Children's Hospital- San Diego

    San Diego, California, 92123, United States

  • St. Jude Children's Research Hospital

    Memphis, Tennessee, 38105, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stanford V chemotherapy (vinblastine, doxorubicin, vincristine, bleomycin, mechlorethamine, etoposide, prednisone) with or without low-dose radiation therapy

What this could lead to

If successful, this could offer a shorter, effective treatment for children with Hodgkin lymphoma, reducing side effects while maintaining high cure rates.

What could go wrong

This is a phase 2 trial with only 88 participants, so results may not apply to all patients. Chemotherapy and radiation carry risks like infection, bleeding, and long-term effects.

Conditions

The condition(s) this trial relates to.

Hodgkins lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.