New hope for kids with tough cancers: daily pill combo aims to shrink tumors

NCT ID NCT02574728

Summary

This study is testing whether a combination of daily oral medications can shrink tumors in children whose cancers have come back or have not responded to standard treatments. The treatment involves taking several pills daily, including sirolimus, celecoxib, and alternating low doses of chemotherapy drugs. The main goal is to see if this approach can reduce tumor size and stop cancer growth in children with solid tumors or brain tumors.

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Contacts and locations

Locations

  • Children's Healthcare of Atlanta, Scottish Rite

    Atlanta, Georgia, 30342, United States

  • Children's Healthcare of Atlanta-Egleston

    Atlanta, Georgia, 30322, United States

  • Children's Mercy Hospital

    Kansas City, Missouri, 64108, United States

  • Nemours/Alfred I. duPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • University of Virginia Health System

    Charlottesville, Virginia, 22908, United States

Conditions

Explore the condition pages connected to this study.