New heart procedure aims to stop persistent AFib in its tracks

NCT ID NCT07541989

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at two ways to treat a type of irregular heartbeat called non-paroxysmal atrial fibrillation (AFib) that doesn't go away on its own. Both methods use a new technique called pulsed-field ablation to destroy tiny areas of heart tissue causing the problem. One group gets standard ablation, while the other gets extra mapping to find and treat additional trouble spots. The goal is to see which approach works better and is safer for the 300 participants over three years.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Changshu Hospital of Traditional Chinese Medicine

    Changshu, Jiangsu, 215516, China

  • Jinan City People's Hospital

    Jinan, Shandong, 271100, China

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine Shanghai

    Shanghai, 200127, China

  • Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine

    Jinan, Shandong, 250001, China

  • Shanghai Jiao Tong University School of Medicine, Shanghai Chest Hospital

    Shanghai, 200030, China

  • The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430014, China

  • Wenling Hospital of Traditional Chinese Medicine

    Wenling, Zhejiang, 317500, China

  • Xuzhou Central Hospital

    Xuzhou, Jiangsu, 221009, China

  • Yuhuan Second People's Hospital

    Yuhuan, Zhejiang, 317600, China