Could a light swab stop nose surgery infections?

NCT ID NCT06731881

Recruiting now Prevention Sponsor: Guy's and St Thomas' NHS Foundation Trust Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study is testing whether a light-activated gel applied inside the nose before surgery can prevent infections afterward. Eighty adults having nasal surgery will either get the light treatment or a plain gel. Researchers will track who needs antibiotics for infection within 30 days. The goal is to see if this simple approach can safely reduce surgical site infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: methylene blue and chlorhexidine solution activated by light (Steriwave device)
What this could lead to: If it works, this could offer a simple, drug-free way to lower infection risk after nasal surgery, reducing the need for antibiotics.
What could go wrong: This is a small, early pilot study (80 people) and is not blinded, so results may be less reliable. The treatment may not significantly reduce infections compared to standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LIGHT; THERAPY, COMPLICATIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

nasal disorder Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LIGHT; THERAPY, COMPLICATIONS NASAL DISEASE SURGERY

Contacts and locations

Locations

Guy's Hospital
RECRUITING

London, London, SE1 9RT, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.