New combo therapy offers hope for cancer patients who Can't breathe

NCT ID NCT06306638

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a two-step treatment for people with advanced cancer that blocks their airways. First, they get low-dose radiation to shrink the tumor. Then, they receive a light-activated drug through an IV, followed by a laser to destroy remaining tumor cells. The goal is to improve breathing and survival with fewer side effects than high-dose radiation alone. About 42 adults with inoperable tumors will participate.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abramson Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

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Other studies related to the condition(s) this trial covers.