New drug cocktail shows promise for Hard-to-Treat myeloma

NCT ID NCT01665794

First seen Jan 07, 2026 · Last updated May 15, 2026 · Updated 25 times

Summary

This study tested a combination of three drugs (pomalidomide, dexamethasone, and carfilzomib) in 25 people whose multiple myeloma had returned or stopped responding to prior treatments. The goal was to find the safest dose and see how well the drugs worked together. Results helped guide further research on adding a fourth drug, daratumumab.

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Contacts and locations

Locations

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • University Health Network - Princess Margaret Cancer Center

    Toronto, Ontario, MISG 2M9, Canada

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637-1470, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • Wayne State University - Karmonos Cancer Center

    Detroit, Michigan, 48201, United States

Conditions

Explore the condition pages connected to this study.