Gene therapy takes on hepatitis b: first human trial launches

NCT ID NCT06680232

Recruiting now Disease control Sponsor: Precision BioSciences, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This early-stage study tests a new gene therapy called PBGENE-HBV in 45 adults with chronic hepatitis B who are already on antiviral medication. The goal is to see if the treatment is safe and can help control the virus. Participants must be in good health and have no liver scarring or other infections.

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Conditions

The condition(s) this trial relates to.

chronic hepatitis B virus infection hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATITIS B CHRONIC

Contacts and locations

Locations

ARENSIA Exploratory Medicine
RECRUITING

Bucharest, Romania, 021105, Romania
Arensia Exploratory Medicine in collaboration with County Clinical Emergency Hospital
RECRUITING

Cluj-Napoca, Romania, 400006, Romania
Hospital Beaujon
RECRUITING

Clichy, France, 92110, France
ICS ARENSIA Exploratory Medicine SRL
RECRUITING

Chisinau, 2025, Moldova
Massachusetts General Hospital/Harvard University
RECRUITING

Boston, Massachusetts, 02114, United States
New Zealand Clinical Research
RECRUITING

Auckland, 1010, New Zealand
Queen Mary Hospital, The University of Hong Kong
RECRUITING

Hong Kong, Hong Kong, Hong Kong

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