New imaging techniques could unmask silent lung damage in mild asthma
NCT ID NCT07143747
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This study explores whether advanced imaging can detect subtle airway abnormalities in young adults with mild asthma that standard tests might miss. Participants will undergo two types of lung imaging—hyperpolarized xenon-129 MRI and Technegas SPECT—along with breathing tests and questionnaires. The goal is to see if these imaging techniques reveal more detailed lung function changes and whether they relate to symptoms and quality of life. Findings could lead to better diagnostic tools and more personalized treatment strategies for mild asthma.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Hyperpolarized 129Xe gas and Tc-99m-labeled carbon aerosol (Technegas) for lung imaging
- What this could lead to
- If successful, this could lead to better diagnostic tools that detect subtle lung abnormalities in mild asthma, enabling more personalized treatment.
- What could go wrong
- This is an observational study with a small sample size, so findings may not apply broadly. The imaging techniques are experimental and may not correlate with symptoms or standard tests.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Robarts Research Institute; The University of Western Ontario
RECRUITINGLondon, Ontario, N6A 5B7, Canada
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