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New asthma inhaler shows promise in large trial

NCT ID NCT02892344

Completed Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new inhaler called QMF149, which combines two drugs (indacaterol and mometasone), against a standard steroid inhaler (mometasone alone) in 802 adults and teens with mild asthma. The goal was to see if the combination improved lung function and symptom control over 12 weeks. Results showed that QMF149 helped patients breathe better and control their asthma more effectively than the standard treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QMF149 (indacaterol acetate and mometasone furoate)

What this could lead to

If successful, this could offer a more effective once-daily inhaler for people with mild asthma, improving lung function and symptom control.

What could go wrong

This is a completed Phase 3 trial, but results may not apply to all asthma patients. The improvement over existing treatment may be modest, and long-term safety data are limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MILD ASTHMA

Contacts and locations

Locations

  • Novartis Investigative Site

    Bulgaria, Bulgaria, Bulgaria

  • Novartis Investigative Site

    Stara Zagora, Bulgaria, 6000, Bulgaria

  • Novartis Investigative Site

    Pleven, 5800, Bulgaria

  • Novartis Investigative Site

    Santiago, Santiago Metropolitan, 7500692, Chile

  • Novartis Investigative Site

    Santiago, 8380453, Chile

  • Novartis Investigative Site

    Santiago, Chile

  • Novartis Investigative Site

    Viña del Mar, 2520594, Chile

  • Novartis Investigative Site

    Medellín, Antioquia, 0050010, Colombia

  • Novartis Investigative Site

    Bucaramanga, Colombia, Colombia

  • Novartis Investigative Site

    Medellín, Colombia, Colombia

  • Novartis Investigative Site

    Bogota, Cundinamarca, 110911, Colombia

  • Novartis Investigative Site

    Bogotá, Colombia

  • Novartis Investigative Site

    Tartu, Estonia, 51014, Estonia

  • Novartis Investigative Site

    Kohtla-Järve, 30322, Estonia

  • Novartis Investigative Site

    Tallinn, 13419, Estonia

  • Novartis Investigative Site

    Tartu, 51014, Estonia

  • Novartis Investigative Site

    Bochum, Germany, 44791, Germany

  • Novartis Investigative Site

    Marburg, Germany, D-35037, Germany

  • Novartis Investigative Site

    Bad Wörishofen, 86825, Germany

  • Novartis Investigative Site

    Berlin, 10119, Germany

  • Novartis Investigative Site

    Darmstadt, 64283, Germany

  • Novartis Investigative Site

    Frankfurt, 60596, Germany

  • Novartis Investigative Site

    Gauting, 82131, Germany

  • Novartis Investigative Site

    Hamburg, 20354, Germany

  • Novartis Investigative Site

    Hanover, 30173, Germany

  • Novartis Investigative Site

    Landsberg, 86899, Germany

  • Novartis Investigative Site

    Leipzig, 04207, Germany

  • Novartis Investigative Site

    Lübeck, 23552, Germany

  • Novartis Investigative Site

    Mainz, 55131, Germany

  • Novartis Investigative Site

    Szarvas, Hungary, 5540, Hungary

  • Novartis Investigative Site

    Szeged, Hungary, 6722, Hungary

  • Novartis Investigative Site

    Győr, HUN, 9024, Hungary

  • Novartis Investigative Site

    Százhalombatta, HUN, 2440, Hungary

  • Novartis Investigative Site

    Törökbálint, Pest County, 2045, Hungary

  • Novartis Investigative Site

    Cegléd, 2700, Hungary

  • Novartis Investigative Site

    Gödöllő, 2100, Hungary

  • Novartis Investigative Site

    Ahmedabad, Gujarat, 380 060, India

  • Novartis Investigative Site

    Vadodara, Gujarat, 390022, India

  • Novartis Investigative Site

    Bangalore, Karnataka, 560099, India

  • Novartis Investigative Site

    Hubli, Karnataka, 580022, India

  • Novartis Investigative Site

    Mysore, Karnataka, 570001, India

  • Novartis Investigative Site

    Cherthala, Kerala, 688524, India

  • Novartis Investigative Site

    Mumbai, Maharashtra, 401107, India

  • Novartis Investigative Site

    Nagpur, Maharashtra, India

  • Novartis Investigative Site

    Bikaner, Rajasthan, 334003, India

  • Novartis Investigative Site

    Coimbatore, Tamil Nadu, 641 045, India

  • Novartis Investigative Site

    Hyderabad, Telangana, 500018, India

  • Novartis Investigative Site

    Varanasi, Uttar Pradesh, 221005, India

  • Novartis Investigative Site

    Cassano delle Murge, BA, 70020, Italy

  • Novartis Investigative Site

    Florence, FI, 50134, Italy

  • Novartis Investigative Site

    Genova, Italy, 16147, Italy

  • Novartis Investigative Site

    Fiumicino, RM, 00054, Italy

  • Novartis Investigative Site

    Roma, 00161, Italy

  • Novartis Investigative Site

    Chuo Ku, Tokyo, 103 0027, Japan

  • Novartis Investigative Site

    Chuo-ku, Tokyo, 103-0027, Japan

  • Novartis Investigative Site

    Setagaya-ku, Tokyo, 157006, Japan

  • Novartis Investigative Site

    Shinjuku-ku, Tokyo, 162-0053, Japan

  • Novartis Investigative Site

    Toshima-ku, Tokyo, 171-0014, Japan

  • Novartis Investigative Site

    Jūrmala, LVA, LV-2015, Latvia

  • Novartis Investigative Site

    Riga, LV, 1011, Latvia

  • Novartis Investigative Site

    Daugavpils, LV-5417, Latvia

  • Novartis Investigative Site

    Riga, LV 1002, Latvia

  • Novartis Investigative Site

    Riga, LV-1001, Latvia

  • Novartis Investigative Site

    Riga, LV-1004, Latvia

  • Novartis Investigative Site

    Vilnius, 8109, Lithuania

  • Novartis Investigative Site

    Vilnius, LT-08661, Lithuania

  • Novartis Investigative Site

    Alor Star, Kedah, 05460, Malaysia

  • Novartis Investigative Site

    Taiping, Perak, 34000, Malaysia

  • Novartis Investigative Site

    Kuala Terengganu, Terengganu, 20400, Malaysia

  • Novartis Investigative Site

    Putrajaya, 62250, Malaysia

  • Novartis Investigative Site

    Santiago de Surco, Lima region, 33, Peru

  • Novartis Investigative Site

    Cusco, 84, Peru

  • Novartis Investigative Site

    Lima, 10, Peru

  • Novartis Investigative Site

    Lima, 14, Peru

  • Novartis Investigative Site

    Piura, 2000, Peru

  • Novartis Investigative Site

    Iloilo City, Iloilo, 5000, Philippines

  • Novartis Investigative Site

    Manila, 1008, Philippines

  • Novartis Investigative Site

    Quezon City, 1100, Philippines

  • Novartis Investigative Site

    Biaystok, Poland, 15-430, Poland

  • Novartis Investigative Site

    Bialystok, 15-044, Poland

  • Novartis Investigative Site

    Grudziądz, 86-300, Poland

  • Novartis Investigative Site

    Katowice, 40 085, Poland

  • Novartis Investigative Site

    Moscow, 115478, Russia

  • Novartis Investigative Site

    Rostov-on-Don, 344011, Russia

  • Novartis Investigative Site

    Saint Petersburg, 191015, Russia

  • Novartis Investigative Site

    Saint Petersburg, 194044, Russia

  • Novartis Investigative Site

    Saint Petersburg, 196240, Russia

  • Novartis Investigative Site

    Yekaterinburg, 620028, Russia

  • Novartis Investigative Site

    Bardejov, Slovak Republic, 085 01, Slovakia

  • Novartis Investigative Site

    Bojnice, Slovak Republic, 972 01, Slovakia

  • Novartis Investigative Site

    Humenné, Slovak Republic, 066 01, Slovakia

  • Novartis Investigative Site

    Liptovský Hrádok, Slovak Republic, 033 01, Slovakia

  • Novartis Investigative Site

    Spišská Nová Ves, Slovak Republic, 052 01, Slovakia

  • Novartis Investigative Site

    Stropkov, Slovak Republic, 09101, Slovakia

  • Novartis Investigative Site

    Čadca, Slovakia, 022 01, Slovakia

  • Novartis Investigative Site

    Prešov, Slovakia, 080 01, Slovakia

  • Novartis Investigative Site

    Zvolen, Slovakia, 960 01, Slovakia

  • Novartis Investigative Site

    Banská Bystrica, SVK, 974 05, Slovakia

  • Novartis Investigative Site

    Poprad, SVK, 058 01, Slovakia

  • Novartis Investigative Site

    Bratislava, 841 04, Slovakia

  • Novartis Investigative Site

    Sabinov, 08301, Slovakia

  • Novartis Investigative Site

    Winnie Mandela, Free State, 8340, South Africa

  • Novartis Investigative Site

    Middelburg, Mpumalanga, 1050, South Africa

  • Novartis Investigative Site

    Belleville, South Africa, 7530, South Africa

  • Novartis Investigative Site

    Cape Town, ZAF, 7570, South Africa

  • Novartis Investigative Site

    Cape Town, 7531, South Africa

  • Novartis Investigative Site

    Panorama, 7550, South Africa

  • Novartis Investigative Site

    Anyang-si, Gyeonggi-do, 14068, South Korea

  • Novartis Investigative Site

    Bucheon-si, Gyeonggi-do, 14584, South Korea

  • Novartis Investigative Site

    Hwaseong-si, Gyeonggi-do, 18450, South Korea

  • Novartis Investigative Site

    Suwon, Gyeonggi-do, 16499, South Korea

  • Novartis Investigative Site

    Seoul, Korea, 03312, South Korea

  • Novartis Investigative Site

    Seoul, Seocho gu, 06591, South Korea

  • Novartis Investigative Site

    Busan, 612-896, South Korea

  • Novartis Investigative Site

    Seoul, 02841, South Korea

  • Novartis Investigative Site

    Stockholm, 111 57, Sweden

  • Novartis Investigative Site

    Uppsala, 75237, Sweden

  • Novartis Investigative Site

    Linköping, Östergötland County, 587 58, Sweden

  • Novartis Investigative Site

    Bangkok, Thailand, 10400, Thailand

  • Novartis Investigative Site

    Khon Kaen, THA, 40002, Thailand

  • Novartis Investigative Site

    Chiang Mai, 50200, Thailand

  • Novartis Investigative Site

    Ho Chi Minh City, VNM, 700000, Vietnam

  • Novartis Investigative Site

    Haiphong, 180000, Vietnam