New study tests if Same-Time radiation and chemo is safe for breast cancer

NCT ID NCT01928589

Ongoing Disease control Sponsor: Richard Zellars Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at women with early-stage breast cancer who need both radiation and chemotherapy after surgery. It compares giving these treatments at the same time versus one after the other, to see if the combined approach has similar side effects and outcomes. About 81 women will take part, with most receiving the new same-time method.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: partial breast irradiation and chemotherapy
What this could lead to: If successful, this could offer a more convenient treatment schedule for early-stage breast cancer patients, potentially reducing the time needed for therapy.
What could go wrong: This is a small, early-phase study (81 participants) comparing two approaches, so results may not apply broadly. There is a risk of increased side effects when combining treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast adenocarcinoma breast cancer breast neoplasm invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADENOCARCINOMA OF THE BREAST BREAST CANCER

Contacts and locations

Locations

IU Health Arnett

Lafayette, Indiana, 47905, United States
Indiana University Health Hospital

Indianapolis, Indiana, 46202, United States
Indiana University Health Melvin and Bren Simon Comprehensive Cancer Center

Indianapolis, Indiana, 46202, United States
John Hopkins University

Baltimore, Maryland, 21218, United States
Parkview Regional Medical Center

Fort Wayne, Indiana, 46845, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Suburban Hospital

Bethesda, Maryland, 20814, United States
University of Texas-San Antonio

San Antonio, Texas, 78229, United States
York Cancer Center

York, Pennsylvania, 17403, United States

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