New PET tracer aims to spot Parkinson's protein in living brains
NCT ID NCT07348250
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times
Summary
This early-phase study tests a new imaging drug called [18F]MK-0947 that works with PET scans to show where a protein called α-synuclein builds up in the brain—a hallmark of Parkinson's disease. Researchers will check safety and how well the tracer works in 22 adults (some with Parkinson's, some healthy). If successful, this could lead to better tools for diagnosing and tracking Parkinson's.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- [18F]MK-0947 (a radioactive imaging drug for PET scans)
- What this could lead to
- If successful, this could lead to a new way to see Parkinson's-related protein buildup in the brain, helping doctors diagnose the disease earlier and track its progression.
- What could go wrong
- This is a very early, small study (22 people) focused on safety and imaging, not treatment. The tracer may not work as hoped, and results may not apply to all Parkinson's patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON'S DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Invicro (dba Perceptive)
New Haven, Connecticut, 06510, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- High-Resolution brain scans aim to unmask Tau's role in Parkinson's
- Can brain stimulation sharpen Decision-Making in Parkinson's?
- Can a new pill slow Parkinson's symptoms?
- Dancing away Parkinson's symptoms: tango therapy put to the test
- Can Stem-Cell implants restore movement in Parkinson's?
- Gentle bowing, calmer mind: music therapy put to the test for Parkinson's anxiety