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Can simple calf raises rewire muscle energy in Parkinson's?

NCT ID NCT07720713

Symptom relief Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial tests whether a four-week home-based strengthening program can improve how calf muscles handle energy in people with Parkinson's disease. Using magnetic resonance spectroscopy, researchers will measure muscle metabolism before and after the program. The study includes both people with Parkinson's and healthy volunteers aged 50 to 80.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a four-week home-based progressive strengthening program using bodyweight exercises
What this could lead to
If successful, this could point toward a simple exercise intervention to improve muscle function in people with Parkinson's disease.
What could go wrong
This is a very small early trial with only 19 participants, so results may not apply broadly. The exercise program is short and home-based, which may limit its impact.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

19 people

The number who actually took part.

Started

Apr 2022

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 50-80 years of age, males and females, individuals with and without PD * Hoehn and Yahr stages 1- 4 (if diagnosed with PD) * Bilateral Heal Raise - minimum of 10 repetitions Exclusion Criteria: * Unable to walk for \>5 minutes at a time with or without an assistive device * Any comorbidity limiting exercise

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Conditions

The condition(s) this trial relates to.

Motor Activity Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson

Contacts and locations

Locations

  • UT Southwestern Medical Center

    Dallas, Texas, 75235, United States

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