New drug trial aims to hit brakes on Parkinson's decline

NCT ID NCT05348785

Ongoing Disease control Sponsor: Biogen Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an experimental drug called BIIB122 can slow down the worsening of Parkinson's disease symptoms. Researchers are enrolling 650 adults with early-stage Parkinson's (diagnosed within 2 years) to take either the drug or a placebo pill daily for 1 to 3 years. The main goal is to see if the drug delays the progression of symptoms that affect movement and daily activities.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AO Universitaria Pisana

Pisa, 56126, Italy
AOU Luigi Vanvitelli

Naples, 80138, Italy
Adventist Health System/Sunbelt, Inc.

Orlando, Florida, 32803, United States
Azienda Ospedaliera Spedali

Brescia, 25123, Italy
Azienda Ospedaliero Universitaria Policlinico 'Gaspare Rodolico - San Marco' (Presidio G. Rodolico)

Catania, 95123, Italy
Banner Sun Health Research Institute

Sun City, Arizona, 85351, United States
Beijing Hospital

Beijing, Beijing Municipality, 100730, China
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Boston University Medical Center

Boston, Massachusetts, 02118, United States
Brain Research Center Amsterdam

Amsterdam, 1081 GN, Netherlands
Brain Research Center Zwolle B.V.

Zwolle, 8025 AZ, Netherlands
CHU Clermont Ferrand - Hopital Gabriel Montpied

Clermont-Ferrand, Puy De Dome, 63003, France
CHU Nantes - Hopital Nord Laën

Loire-Atlantique, Loire-Atlantique, 44093, France
CHU Rennes - Hopital Pontchaillou

Rennes, Ille Et Vilaine, 35033, France
CHUM Centre de Recherche

Montreal, Quebec, H2L 4M1, Canada
Cedars Sinai

Los Angeles, California, 90048, United States
CenExel Rocky Mountain Clinical Research

Englewood, Colorado, 80113, United States
Center Chaim Sheba Medical Center

Ramat Gan, 5262000, Israel
Central Texas Neurology Consultants

Round Rock, Texas, 78681, United States
Centre Hospitalier Universitaire de Lyon-Hospices Civils de Lyon-Hopital Pierre Wertheimer

Bron, Rhone, 69500, France
Centrum Medyczne Neuromed

Bydgoszcz, 85-163, Poland
Charing Cross Hospital

London, Greater London, W6 8RF, United Kingdom
Clinica Universidad de Navarra

Pamplona, Navarre, 31008, Spain
Complejo Hospitalario Universitario A Coruña

A Coruña, 15006, Spain
Duke Movement Disorders Clinic

Durham, North Carolina, 27705, United States
Evergreen Hospital Medical Center

Kirkland, Washington, 98034, United States
Fondazione

Milan, 20122, Italy
Groupe Hospitalier Pitie-Salpetriere

Paris, 75013, France
Hawaii Pacific Neuroscience, LLC

Honolulu, Hawaii, 96817, United States
Himeji Central

Himeji-shi, 672-8043, Japan
Hopital Gui de Chauliac

Montpellier, Herault, 34295, France
Hopital Henri Mondor

Paris, 94010, France
Hopital Purpan

Toulouse, Haute Garonne, 31059, France
Hospital Clinic de Barcelona

Barcelona, 8036, Spain
Hospital General de Catalunya

Sant Cugat del Vallès, Barcelona, '08190, Spain
Hospital Universitari Vall d'Hebron

Barcelona, 08035, Spain
Hospital Universitario Marques

Santanda, Santanda, 38003, Spain
Hospital Universitario Virgen del Rocio

Seville, 41013, Spain
Hospital Universitario de La Princesa

Madrid, 28006, Spain
Hospital de Cruces

Barakaldo, 48903, Spain
Hospital de la Santa Creu i Sant Pau

Barcelona, 08041, Spain
Hôpital de la Timone

Marseille, Bouches-du-Rhône, 13005, France
I.R.C.C.S. Neuromed

Diego, Centonze, 86077, Italy
INSULA Centrum Badan Klinicznych

Warsaw, 02-699, Poland
IRCCS San Raffaele Pisana

Roma, 00163, Italy
IRCCS-Institute of Neurological Sciences of Bologna

Bologna, 40139, Italy
Inland Northwest Research

Spokane, Washington, 99202, United States
Instytut Zdrowia dr Boczarska-Jedynak sp.z.o.o, Sp.K

Oświęcim, Katowice, 32-600, Poland
Invicro

New Haven, Connecticut, 06510, United States
Juntendo University

Tokyo, 113-8431, Japan
Katholisches Klinikum Bochum gGmbH

Bochum, North Rhine-Westphalia, 44791, Germany
Klinik Ottakring

Vienna, 1160, Austria
Klinikum der Universität München

Munich, Bavaria, 81377, Germany
Klinikum rechts der Isar der TU Muenchen

Munich, Bavaria, 81675, Germany
MD Clinic Praga

Warsaw, 03-505, Poland
Massachusetts General Hospital

Boston, Massachusetts, 02421, United States
Mayo Clinic Arizona

Phoenix, Arizona, 85054, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Medizinische Hochschule Hannover

Hanover, Lower Saxony, 30625, Germany
Medizinische Universität

Innsbruck, Tyrol, 6020, Austria
Montreal Neurological Institute

Montreal, Quebec, H3A 2B4, Canada
Mount Sinai Beth Israel

New York, New York, 10003, United States
NHO Asahikawa Medical Center

Asahikawa-shi, 070-8644, Japan
NeuroClin Limited

Motherwell, Strathclyde, ML1 4UF, United Kingdom
NeuroProtect Sp. z o.o.

Warsaw, Masovian Voivodeship, 01-684, Poland
Neurology Clinic, PC

Cordova, Tennessee, 38018, United States
Newcastle University

Newcastle upon Tyne, Tyne and Wear, NE4 5PL, United Kingdom
Ninewells Hospital

Dundee, DD1 9SY, United Kingdom
Northwestern University

Chicago, Illinois, 60611, United States
Nzoz Novo-Med

Katowice, 40-650, Poland
Okinawa Prefectural Nanbu

Haeburu, Okinawa, 901-1105, Japan
Ospedale Clinicizzato SS. Annu

Chieti, 66100, Italy
Ospedale San Raffaele

Milan, 20132, Italy
Paracelsus-Elena-Klinik Kassel

Kassel, Hesse, 34128, Germany
Parkinson's Disease and Movement Disorders Center of Boca Raton

Boca Raton, Florida, 33486, United States
Philipps University of Marburg

Marburg, Hesse, 35043, Germany
Policlinica Gipuzkoa

Donostia / San Sebastian, 20014, Spain
Quest Research Institute

Farmington Hills, Michigan, 48334, United States
Rabin Medical Center

Petah Tikva, 4941492, Israel
Radboudumc

Nijmegen, 6525 GA, Netherlands
Re:Cognition Health - Birmingham

Birmingham, West Midlands, B16 8LT, United Kingdom
Re:Cognition Health Ltd (London)

London, Greater London, W1G 9RU, United Kingdom
Rush University Medical Center

Chicago, Illinois, 60612, United States
SC3 Research Group Inc.

Pasadena, California, 91105, United States
Salford Royal NHS Foundation Trust

Salford, Greater Manchester, M6 8HD, United Kingdom
Second Affiliated Hospital of Soochow University

Jiangsu, Jiangsu, 215004, China
Sendai Nishitaga National Hospital

Sendai, 982-8555, Japan
Tazuke-kofukai Medical Research Institute Kitano Hospital

Osaka, Osaka, 530-8480, Japan
Tel Aviv Sourasky Medical Center

Tel Aviv, 6423906, Israel
The Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
The Methodist Hospital Research Institute

Houston, Texas, 77030, United States
The National Hospital for Neurology & Neurosurgery

London, Greater London, WC1N 3BG, United Kingdom
Toronto Western Hospital

Toronto, Ontario, M5T 2S8, Canada
True North Clinical Research

Halifax, Nova Scotia, B3S 1M7, Canada
UPHS

Philadelphia, Pennsylvania, 19107, United States
USF Health Byrd Institute

Tampa, Florida, 33613, United States
Universitaetsklinikum Carl Gustav Carus TU Dresden

Dresden, Saxony, 01307, Germany
Universitaetsklinikum Duesseldorf AoeR

Düsseldorf, North Rhine-Westphalia, 40225, Germany
Universitaetsklinikum Schleswig-Holstein - Campus Luebeck

Lübeck, Schleswig-Holstein, 23538, Germany
Universitaetsklinikum Tuebingen

Tübingen, Baden-Wurttemberg, 72076, Germany
Universitaetsklinikum Ulm

Ulm, Baden-Wurttemberg, 89081, Germany
Universitaetsklinikum Wuerzburg

Würzburg, Bavaria, 97080, Germany
University Hospitals Plymouth

Plymouth, Devon, PL6 8DH, United Kingdom
University of Calgary

Calgary, Alberta, T2N 1N4, Canada
University of California San Francisco (UCSF)

San Francisco, California, 94143, United States
University of Colorado

Aurora, Colorado, 80045, United States
University of Kansas Medical Center Research Institute, Inc.

Kansas City, Kansas, 66160, United States
University of Miami

Miami, Florida, 33136, United States
University of Southern California

Los Angeles, California, 90033, United States
Virginia Commonwealth University Department of Neurology

Richmond, Virginia, 23298, United States
Weill Medical College of Cornell University

New York, New York, 10021, United States
West China Hospital, Sichuan University

Chengdu, Sichuan, 610041, China
Xuanwu Hospital Capital Medical University

Beijing, Beijing Municipality, 100053, China

Conditions

Explore the condition pages connected to this study.

PARKINSON DISEASE