Can a Pre-Procedure painkiller ease the pain of lung nodule marking?

NCT ID NCT07675473

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This trial tests whether giving the painkiller parecoxib before a CT-guided wire placement can reduce pain during lung nodule localization for surgery. About 150 adults with lung cancer scheduled for video-assisted thoracoscopic surgery will receive either parecoxib or a placebo before the wire placement. Researchers will also explore the best timing for the medication to maximize pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

parecoxib sodium

What this could lead to

If effective, this could establish a simple, non-opioid pain relief strategy for patients undergoing lung nodule localization before surgery.

What could go wrong

This is a single-center, Phase 4 trial with 150 participants, so results may not apply broadly. The placebo group also receives no active painkiller, so pain differences may be small.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Chest Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••