New Immune-Targeting drug tested in fight against deadly pancreatic cancer

NCT ID NCT03816163

Ongoing Disease control Sponsor: Astellas Pharma Global Development, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing if adding a new drug called zolbetuximab to standard chemotherapy helps people with advanced pancreatic cancer that has spread. The drug works by targeting a specific protein found on many pancreatic cancer cells, aiming to help the immune system attack the tumor. About 393 adults who have not had prior chemotherapy for their metastatic cancer will be randomly assigned to receive either the new drug combination or chemotherapy alone. The main goals are to see if the combination helps people live longer and to check its safety.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Baptist Health

Miami, Florida, 33176, United States
Cancer Treatment Centers of Atlanta

Newnan, Georgia, 30265, United States
David C Pratt Cancer Center

Creve Coeur, Missouri, 63141, United States
Houston Methodist Hospital

Houston, Texas, 77030, United States
Lynn Cancer Institute

Boca Raton, Florida, 33486, United States
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
Memorial Sloan-Kettering Cancer Center

New York, New York, 10022, United States
Midstate Medical Center

Meriden, Connecticut, 06451, United States
MultiCare Regional Cancer Center - Gig Harbor

Gig Harbor, Washington, 98335, United States
Northwell Health Cancer Institute

Lake Success, New York, 11042, United States
Norton Cancer Institute (NCI)

Louisville, Kentucky, 40202, United States
Novant Health

Winston-Salem, North Carolina, 27103, United States
Novant Health Presbyterian Medical Center

Charlotte, North Carolina, 28204, United States
Ochsner Health System

New Orleans, Louisiana, 70121, United States
Roswell Park Cancer Institute

Buffalo, New York, 14203, United States
Site AU61005

Fitzroy, Victoria, 5XRF+WX, Australia
Site AU61006

Warrnambool, Victoria, VIC 3280, Australia
Site AU61007

Wollongong, New South Wales, HVGM+3C, Australia
Site AU61008

Gosford, New South Wales, NSW 2250, Australia
Site BR55004

Santa Catarina, Brazil
Site BR55008

Rio Grande, Brazil
Site BR55009

Centro Passo Fundo, Brazil
Site BR55010

São Paulo, Brazil
Site BR55011

São Paulo, Brazil
Site BR55012

Porto Alegre, Rio Grande do Sul, Brazil
Site CN86001

Beijing, China
Site CN86002

Hubei, China
Site CN86003

Zhejiang, China
Site CN86004

Guangdong, China
Site CN86005

Jiangsu, China
Site CN86006

Shanghai, China
Site CN86007

Tianjin, China
Site CN86008

Beijing, China
Site CN86009

Chongqing, China
Site CN86010

Zhengzhou, China
Site CN86011

Jiangsu, China
Site CN86012

Harbin, China
Site CN86013

Shanghai, China
Site CN86014

Beijing, China
Site CN86016

Guangzhou, China
Site CN86018

Zhejiang, China
Site CN86019

Shanghai, China
Site CN86020

Guangdong, China
Site CN86022

Xinjiang, China
Site CN86023

Shandong, China
Site CN86024

Yanxi, China
Site CN86025

Jiangsu, China
Site CN86026

Changchun, China
Site ES34003

Pamplona, Navarre, 31008, Spain
Site ES34004

Llobregat, Barcelona, 08908, Spain
Site ES34005

Lleida, 25198, Spain
Site ES34006

Madrid, 28033, Spain
Site ES34007

Barcelona, 08916, Spain
Site ES34009

Madrid, 28034, Spain
Site ES34010

Barcelona, 08028, Spain
Site ES34013

Barcelona, 08036, Spain
Site ES34014

Cáceres, 10003, Spain
Site ES34015

Madrid, 28027, Spain
Site ES34017

Santiago de Compostela, Spain
Site ES34018

Barcelona, Spain
Site ES34021

Barcelona, Spain
Site ES34022

Córdoba, Spain
Site ES34026

Málaga, Spain
Site FR33001

Bayonne, 64109, France
Site FR33002

Grenoble, France
Site FR33003

Aquitaine, Pessac, 33604, France
Site FR33005

Pringy, 74374, France
Site FR33006

Chambray, Cedex 9, 37170, France
Site FR33007

Strasbourg, 67000, France
Site FR33008

Besançon, Besancon Cedex, 6XG7+42, France
Site FR33009

Nancy, Nancy Cedex, 54000, France
Site FR33010

Brest, Brest Cedex, 9GV7+4G, France
Site FR33012

Herblain, Herblain Cedex, 44805, France
Site FR33013

Villejuif, Villejuif Cedex, 94805, France
Site FR33014

Plérin, 22190, France
Site FR33015

Caen, Cedex 5, 14076, France
Site FR33016

La Chaussée-Saint-Victor, Loir-et-Cher, 41260, France
Site FR33017

Rouen, Normandy, 76000, France
Site FR33018

Bordeaux, France
Site FR33019

La Roche-sur-Yon, France
Site FR33021

Nice, France
Site FR33023

Pierre-Bénite, France
Site IR35301

Elm Park, Dublin, D04 T6F4, Ireland
Site IT39002

Cremona, 26100, Italy
Site IT39003

Milan, 20141, Italy
Site IT39004

Candiolo, Torino, 10060, Italy
Site IT39006

Rozzano, Milan, 20089, Italy
Site IT39008

Veneto, Italy
Site IT39010

Lombardia, Italy
Site IT39014

Toscana, Italy
Site JP81001

Kashiwa, Chiba, Japan
Site JP81002

Shinjuku-ku, Tokyo, Japan
Site JP81003

Kashihara, Nara, Japan
Site JP81004

Fukuoka, Japan
Site JP81005

Sapporo, Hokkaido, Japan
Site JP81006

Yokohama, Kanagawa, Japan
Site JP81007

Nagoya, Aichi-ken, Japan
Site JP81009

Wakayama, Japan
Site JP81010

Osaka, Japan
Site JP81011

Bunkyo-ku, Tokyo, Japan
Site JP81012

Chuo-ku, Tokyo, Japan
Site JP81013

Mitaka, Tokyo, Japan
Site JP81014

Koto-ku, Tokyo, Japan
Site JP81015

Ube, Yamaguchi, Japan
Site KR82001

Seoul, 03080, South Korea
Site KR82002

Seoul, F3QP+76, South Korea
Site KR82003

Seoul, 120-752, South Korea
Site KR82004

Seoul, 138-736, South Korea
Site KR82005

Seongnam-si, Gyeonggi-do, 013620, South Korea
Site KR82006

Seoul, G234+36, South Korea
Site KR82007

Seoul, 152-703, South Korea
Site KR82008

Suwon, Gyeonggi-do, South Korea
Site KR82009

Gyeonggi-do, South Korea
Site KR82010

Daegu, South Korea
Site MX52003

San Luis Potosí City, Mexico
Site MX52004

Distrito Federal, Mexico
Site MX52005

Veracruz, Mexico
Site TR90001

Konya, Turkey (Türkiye)
Site TR90002

Istanbul, Turkey (Türkiye)
Site TR90003

Diyarbakır, Turkey (Türkiye)
Site TR90004

Ankara, Turkey (Türkiye)
Site TR90006

Ankara, Turkey (Türkiye)
Site TW88601

Taipei, 4G9C+W3, Taiwan
Site TW88602

Taichung, 5M5J+36, Taiwan
Site TW88608

New Taipei City, Taiwan
Site TW88609

Taipei, Taiwan
St. Joseph Heritage Medical Group

Fullerton, California, 92835, United States
TOI Clinical research

Whittier, California, 90603, United States
University of Illinois at Chicago

Chicago, Illinois, 60612, United States
Utah Cancer Specialists

Salt Lake City, Utah, 84106, United States
Virginia Mason

Seattle, Washington, 98101, United States
Vista Oncology

Olympia, Washington, 98502, United States

Conditions

Explore the condition pages connected to this study.

METASTATIC PANCREATIC ADENOCARCINOMA METASTATIC PANCREATIC CANCER PANCREATIC CANCER