New combo therapy aims to boost immune fight against pancreatic cancer

NCT ID NCT05846516

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This study tests a new immunotherapy for adults with advanced pancreatic cancer. The treatment uses a special protein and virus to help the immune system kill cancer cells, combined with another drug called ezabenlimab. The goal is to find a safe dose and see if the combination can help people live longer without the cancer growing. About 58 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asklepios Kliniken Hamburg GmbH

    Hamburg, 22763, Germany

  • Centre Hospitalier Universitaire Vaudois (CHUV)

    Lausanne, 1011, Switzerland

  • Clara Campal Comprehesive Cancer Center

    Madrid, 28050, Spain

  • Hopitaux Universitaires de Geneve (HUG)

    Geneva, CH-1205, Switzerland

  • Hospital General Universitario Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • Hospital Universitario Reina Sofía

    Córdoba, 14004, Spain

  • Institut Curie Saint-Cloud

    Saint-Cloud, 92210, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island

    New York, New York, 10016, United States

  • START South Texas Accelerated Research Therapeutics, LLC

    San Antonio, Texas, 78229, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University Hospital Bern

    Bern, 3010, Switzerland

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California Los Angeles

    Santa Monica, California, 90404, United States

  • University of Colorado Cancer Center

    Aurora, Colorado, 80045, United States

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • Universitätsklinikum Heidelberg

    Heidelberg, 69120, Germany

  • Virginia Cancer Specialists, PC

    Fairfax, Virginia, 22031, United States

  • Virginia Mason Medical Center

    Seattle, Washington, 98101, United States

Conditions

Explore the condition pages connected to this study.