New vaccine-antibody combo takes on pancreatic cancer
NCT ID NCT05846516
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 5 times
Summary
This study tests a new immunotherapy for adults with advanced pancreatic cancer. The treatment uses a special protein and virus to help the immune system kill cancer cells, combined with an antibody called ezabenlimab. The goal is to find a safe dose and see if the combination can improve survival compared to standard care. About 58 participants will be enrolled.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asklepios Kliniken Hamburg GmbH
Hamburg, 22763, Germany
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Centre Hospitalier Universitaire Vaudois (CHUV)
Lausanne, 1011, Switzerland
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Clara Campal Comprehesive Cancer Center
Madrid, 28050, Spain
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Hopitaux Universitaires de Geneve (HUG)
Geneva, CH-1205, Switzerland
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Hospital General Universitario Gregorio Marañón
Madrid, 28007, Spain
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario Fundacion Jimenez Diaz
Madrid, 28040, Spain
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Hospital Universitario Reina Sofía
Córdoba, 14004, Spain
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Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
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Orlando Health Cancer Institute
Orlando, Florida, 32806, United States
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Perlmutter Cancer Center at NYU Langone Hospital - Long Island
New York, New York, 10016, United States
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START South Texas Accelerated Research Therapeutics, LLC
San Antonio, Texas, 78229, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University Hospital Bern
Bern, 3010, Switzerland
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of California Los Angeles
Santa Monica, California, 90404, United States
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University of Colorado Cancer Center
Aurora, Colorado, 80045, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Southern California
Los Angeles, California, 90033, United States
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Virginia Cancer Specialists, PC
Fairfax, Virginia, 22031, United States
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Virginia Mason Medical Center
Seattle, Washington, 98101, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can pancreatic Cancer's inflammatory footprint be stopped?
- Blood and gut clues may flag pancreatic cancer risk early
- Can a new drug combo shrink Hard-to-Treat tumors?
- Can a pill outsmart Tumors' defenses?
- A sound wave that could expose hidden pancreatic cancer?
- Can a new immunotherapy combo shrink Hard-to-Treat tumors?