Experimental enzyme targets tough pancreatic tumors
NCT ID NCT02921022
Summary
This study tests whether adding an experimental drug called PEGPH20 to standard chemotherapy helps control advanced pancreatic cancer. PEGPH20 works by breaking down a substance called hyaluronan that pancreatic tumors produce, which may help shrink tumors. The research involves 110 people with advanced pancreatic cancer and focuses on both treatment effectiveness and safety risks, particularly blood clot side effects.
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Contacts and locations
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Locations
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Hartford Healthcare Cancer Institute @ Hartford Hospital
Hartford, Connecticut, 06102, United States
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Lehigh Valley Health Network
Allentown, Pennsylvania, 18103, United States
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Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey, United States
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Memorial Sloan Kettering Bergen
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States
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Miami Cancer Institute
Miami, Florida, 33143, United States
Conditions
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