New hope for tough pancreatic cancer: trial targets specific genetic flaw

NCT ID NCT07409272

Summary

This study is testing whether adding a new drug called setidegrasib to standard chemotherapy helps people with advanced pancreatic cancer that has a specific genetic change (KRAS G12D mutation) live longer. About 614 adults whose cancer has spread and cannot be cured by surgery will be randomly assigned to receive either the new drug or a placebo alongside their chemotherapy. The main goal is to see if the combination extends survival and delays cancer progression compared to chemotherapy alone.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baptist MD Anderson Cancer Institute

    RECRUITING

    Jacksonville, Florida, 32207, United States

  • HealthPartners Cancer Center at Regions Hospital

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

  • HealthPartners Frauenshuh Cancer Center

    RECRUITING

    Saint Louis Park, Minnesota, 55426, United States

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    RECRUITING

    New York, New York, 10016, United States

  • NYU Long Island Mineola

    RECRUITING

    Mineola, New York, 11501, United States

  • Utah Cancer Specialists

    RECRUITING

    Salt Lake City, Utah, 84106, United States

  • Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.