New hope for tough pancreatic cancers: experimental drug combo enters human testing
NCT ID NCT05685602
Summary
This early-stage trial is testing whether adding a new oral drug called CA-4948 to standard chemotherapy is safe and tolerable for people with advanced pancreatic cancer that has spread or cannot be removed by surgery. The main goal is to find the highest dose that patients can handle without severe side effects. Researchers will also watch to see if this three-drug combination can shrink tumors or slow the cancer's growth.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center
ACTIVE_NOT_RECRUITINGDuarte, California, 91010, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
RECRUITINGBaltimore, Maryland, 21287, United States
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
RECRUITINGNew York, New York, 10016, United States
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Memorial Hospital East
RECRUITINGShiloh, Illinois, 62269, United States
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
SUSPENDEDNew York, New York, 10032, United States
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NYU Langone Hospital - Long Island
RECRUITINGMineola, New York, 11501, United States
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National Cancer Institute Developmental Therapeutics Clinic
RECRUITINGBethesda, Maryland, 20892, United States
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National Institutes of Health Clinical Center
ACTIVE_NOT_RECRUITINGBethesda, Maryland, 20892, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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Siteman Cancer Center at Christian Hospital
RECRUITINGSt Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
RECRUITINGCity of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
RECRUITINGCreve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
RECRUITINGOrange, California, 92868, United States
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UCHealth University of Colorado Hospital
RECRUITINGAurora, Colorado, 80045, United States
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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
RECRUITINGIrvine, California, 92612, United States
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UNC Lineberger Comprehensive Cancer Center
SUSPENDEDChapel Hill, North Carolina, 27599, United States
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University of Cincinnati Cancer Center-UC Medical Center
RECRUITINGCincinnati, Ohio, 45219, United States
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University of Cincinnati Cancer Center-West Chester
RECRUITINGWest Chester, Ohio, 45069, United States
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University of Kentucky/Markey Cancer Center
RECRUITINGLexington, Kentucky, 40536, United States
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University of Oklahoma Health Sciences Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh Cancer Institute (UPCI)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
RECRUITINGMadison, Wisconsin, 53718, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
RECRUITINGMadison, Wisconsin, 53792, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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