Tailored chemo after surgery could boost pancreatic cancer survival

NCT ID NCT07044453

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving different chemotherapy drugs after pancreatic cancer surgery, based on how much tumor remains, can improve survival. About 390 patients who received chemo before surgery will be randomly assigned to one of two drug regimens. The goal is to reduce cancer recurrence and extend life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Gemcitabine with Nab-Paclitaxel or mFOLFIRINOX (chemotherapy drugs)
What this could lead to
If successful, this could lead to a more personalized chemotherapy plan after pancreatic cancer surgery, potentially reducing recurrence and improving survival.
What could go wrong
This is an early-phase trial (Phase 2/3) with only 390 participants, so results may not apply to all patients. Chemotherapy side effects can be severe, and the approach may not significantly improve outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Rouen

    RECRUITING

    Rouen, France

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