New trial aims to match sepsis treatments to Patients' unique traits

NCT ID NCT06381661

First seen Jan 29, 2026 · Last updated Jun 20, 2026 · Updated 19 times

Summary

This study tests whether giving sepsis patients drugs tailored to their specific biological traits can improve survival and reduce the need for life support. It will enroll 2000 adults and children across multiple countries, using an adaptive platform to test several treatments at once. The goal is to move away from one-size-fits-all sepsis care toward more personalized medicine.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tocilizumab, Baricitinib, Anakinra, Hydrocortisone

What this could lead to

If successful, this could show that matching sepsis treatments to individual patient traits improves survival and reduces time on life support.

What could go wrong

This is an early Phase 2 exploratory trial, so results may not confirm effectiveness. The complex adaptive design may also make it harder to draw clear conclusions.

Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.