New hope for Hard-to-Treat cancers: targeted pill attacks genetic weakness

NCT ID NCT06390839

First seen Oct 31, 2025 · Last updated May 01, 2026 · Updated 21 times

Summary

This study tests a pill called palbociclib in people with advanced cancers that have extra copies of the CDK4 or CDK6 genes. The drug blocks signals that make cancer cells multiply. Researchers want to see if it can shrink tumors or stop them from growing for at least 6 months. About 43 adults with various cancer types are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.