New drug duo aims to shrink breast tumors before surgery

NCT ID NCT05069038

First seen Dec 29, 2025 · Last updated May 10, 2026 · Updated 16 times

Summary

This study tests whether giving a targeted drug (palbociclib) along with hormone therapy before surgery can shrink tumors in people with early-stage hormone receptor-positive, HER2-negative breast cancer. About 51 participants will receive the combination for several weeks before their operation. The goal is to improve surgical outcomes and understand how well the treatment works.

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Contacts and locations

Locations

  • Unversity of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.