Can we wake and kill sleeping breast cancer cells? new trial aims to find out
NCT ID NCT04841148
First seen Apr 14, 2026 · Last updated Apr 26, 2026 · Updated 4 times
Summary
This study tests whether adding a drug called palbociclib to either hydroxychloroquine or avelumab can eliminate dormant breast cancer cells hiding in the bone marrow. These cells can cause cancer to return years later. The trial involves 96 people with early-stage ER+ breast cancer who still have these hidden cells after standard treatment. The goal is to see if these combinations can clear the cells and reduce the risk of recurrence.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
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Georgetown University
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact Email: •••••@•••••
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Email: •••••@•••••
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Washington
RECRUITINGSeattle, Washington, 98195, United States
Contact Email: •••••@•••••
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Vanderbilt University
RECRUITINGNashville, Tennessee, 37232, United States
Contact Email: •••••@•••••
Conditions
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