Can we wake and kill sleeping breast cancer cells? new trial aims to find out
NCT ID NCT04841148
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for people with early-stage ER+ breast cancer who still have hidden cancer cells in their bone marrow after surgery and standard therapy. It tests whether adding drugs like hydroxychloroquine or avelumab, with or without palbociclib, can clear those leftover cells and lower the risk of the cancer coming back. About 96 participants will be assigned to different treatment groups to see which approach works best and is safe.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
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Georgetown University
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact Email: •••••@•••••
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Email: •••••@•••••
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Washington
RECRUITINGSeattle, Washington, 98195, United States
Contact Email: •••••@•••••
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Vanderbilt University
RECRUITINGNashville, Tennessee, 37232, United States
Contact Email: •••••@•••••