Can retraining the brain ease chronic pain? small trial hopes to find out

NCT ID NCT07287072

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests Pain Reprocessing Therapy (PRT) for adults with chronic primary pain that may be due to a nociplastic pain mechanism. PRT includes education to reframe pain as a false alarm and specific techniques to reduce it. The trial involves 12 participants in Norwegian primary care and measures pain intensity and physical function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pain Reprocessing Therapy (behavioral intervention)
What this could lead to
If successful, this could offer a new, effective treatment option for chronic pain patients in primary care, potentially reducing the need for specialist referrals.
What could go wrong
This is a very small pilot study with only 12 participants, so results may not apply broadly. The therapy is new and its long-term benefits are unknown.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Nociplastic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ullevål sykehus

    Oslo, Norway

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